top-down PTM

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Published By MelissaGeorge


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  •  TypeNew




Top-Down MS is powerful for comprehensive analysis of protein modifications because Top-Down MS is able to analyze intact proteins/peptides without proteolysis. Therefore, the strategy can preserve the labile modified motifs which are mostly lost when shotgun method is applied and CID is used for fragmentation in analysis of protein therapeutics, such as monoclonal antibodies and recombinant proteins. top-down PTM

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